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affinity purified polyclonal antibody against β amyloid  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc affinity purified polyclonal antibody against β amyloid
    Regional and cellular distribution of GABA B1 in wild‐type and APP/PS1 mice . A‐H . Immunoreactivity for GABA B1 in the hippocampus of wild‐type and APP/PS1 mice at 12 months of age using a pre‐embedding immunoperoxidase method at the light microscopic level. In the CA1 and CA3 regions and dentate gyrus (DG), GABA B1 immunoreactivity was very similar both in the wild‐type and the APP/PS1 mice, regardless of accumulation <t>of</t> <t>amyloid</t> plaques (asterisks). Labeling for GABA B1 showed the highest intensity in the stratum lacunosum‐moleculare (slm) and molecular layer (ml) and weaker in the strata oriens (so) and radiatum (sr). Immunoreactivity for GABA B1 was also detected in interneurons throughout all layers (white arrows), with similar distribution pattern and labeling intensity in wild‐type and APP/PS1 mice. I,J . Immunoreactivity for β‐amyloid in wild‐type and APP/PS1 mice at 12 months of age, showing high accumulation of Aβ throughout all layers of the hippocampus. Abbreviations : CA1 region of the hippocampus; CA3, CA3 region of the hippocampus; DG, dentate gyrus; so, stratum oriens ; sp, stratum pyramidale ; sr, stratum radiatum ; slm, stratum lacunosum‐moleculare ; ml, molecular layer; gc, granule cell layer; h, hilus. Scale bars: A,B,I,J 200 µm; C‐H , 100 µm.
    Affinity Purified Polyclonal Antibody Against β Amyloid, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 205 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/affinity+purified+polyclonal+antibody+against+%CE%B2+amyloid/beta-Amyloid+Antibody/pmc07317930-46-1-20
    Average 95 stars, based on 205 article reviews
    affinity purified polyclonal antibody against β amyloid - by Bioz Stars, 2026-10
    95/100 stars

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    1) Product Images from "Reduction in the neuronal surface of post and presynaptic GABA B receptors in the hippocampus in a mouse model of Alzheimer's disease"

    Article Title: Reduction in the neuronal surface of post and presynaptic GABA B receptors in the hippocampus in a mouse model of Alzheimer's disease

    Journal: Brain Pathology

    doi: 10.1111/bpa.12802

    Regional and cellular distribution of GABA B1 in wild‐type and APP/PS1 mice . A‐H . Immunoreactivity for GABA B1 in the hippocampus of wild‐type and APP/PS1 mice at 12 months of age using a pre‐embedding immunoperoxidase method at the light microscopic level. In the CA1 and CA3 regions and dentate gyrus (DG), GABA B1 immunoreactivity was very similar both in the wild‐type and the APP/PS1 mice, regardless of accumulation of amyloid plaques (asterisks). Labeling for GABA B1 showed the highest intensity in the stratum lacunosum‐moleculare (slm) and molecular layer (ml) and weaker in the strata oriens (so) and radiatum (sr). Immunoreactivity for GABA B1 was also detected in interneurons throughout all layers (white arrows), with similar distribution pattern and labeling intensity in wild‐type and APP/PS1 mice. I,J . Immunoreactivity for β‐amyloid in wild‐type and APP/PS1 mice at 12 months of age, showing high accumulation of Aβ throughout all layers of the hippocampus. Abbreviations : CA1 region of the hippocampus; CA3, CA3 region of the hippocampus; DG, dentate gyrus; so, stratum oriens ; sp, stratum pyramidale ; sr, stratum radiatum ; slm, stratum lacunosum‐moleculare ; ml, molecular layer; gc, granule cell layer; h, hilus. Scale bars: A,B,I,J 200 µm; C‐H , 100 µm.
    Figure Legend Snippet: Regional and cellular distribution of GABA B1 in wild‐type and APP/PS1 mice . A‐H . Immunoreactivity for GABA B1 in the hippocampus of wild‐type and APP/PS1 mice at 12 months of age using a pre‐embedding immunoperoxidase method at the light microscopic level. In the CA1 and CA3 regions and dentate gyrus (DG), GABA B1 immunoreactivity was very similar both in the wild‐type and the APP/PS1 mice, regardless of accumulation of amyloid plaques (asterisks). Labeling for GABA B1 showed the highest intensity in the stratum lacunosum‐moleculare (slm) and molecular layer (ml) and weaker in the strata oriens (so) and radiatum (sr). Immunoreactivity for GABA B1 was also detected in interneurons throughout all layers (white arrows), with similar distribution pattern and labeling intensity in wild‐type and APP/PS1 mice. I,J . Immunoreactivity for β‐amyloid in wild‐type and APP/PS1 mice at 12 months of age, showing high accumulation of Aβ throughout all layers of the hippocampus. Abbreviations : CA1 region of the hippocampus; CA3, CA3 region of the hippocampus; DG, dentate gyrus; so, stratum oriens ; sp, stratum pyramidale ; sr, stratum radiatum ; slm, stratum lacunosum‐moleculare ; ml, molecular layer; gc, granule cell layer; h, hilus. Scale bars: A,B,I,J 200 µm; C‐H , 100 µm.

    Techniques Used: Labeling

    Related Articles

    Affinity Purification:

    Article Title: Reduction in the neuronal surface of post and presynaptic GABA B receptors in the hippocampus in a mouse model of Alzheimer's disease
    Article Snippet: A monoclonal anti‐α‐Tubulin (DM1A; ref CP06) was obtained from Millipore (Millipore Corporation, Burlington, MA, USA). .. An affinity‐purified polyclonal antibody against β‐amyloid (ref #2454, detecting human Aβ‐40 and Aβ‐42 peptides) raised in rabbit was obtained from Cell Signalling Technology (Leiden, The Netherlands). .. The secondary antibodies used were as follows: goat anti‐mouse IgG‐horseradish peroxidase (1:2000; Santa Cruz Biotechnology, Santa Cruz, CA, USA), goat anti‐rabbit IgG‐horseradish peroxidase (1:15 000; Pierce, Rockford, USA), alkaline phosphatase AP‐goat anti‐mouse IgG (H + L) and AP‐goat anti‐rabbit IgG (H + L) (1:5000; Invitrogen, Paisley, UK), goat anti‐rabbit IgG coupled to 1.4 nm gold (1:100; Nanoprobes Inc., Stony Brook, NY, USA) and anti‐rabbit IgG conjugated to 10 nm gold particles (1:100; British Biocell International, Cardiff, UK).



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    affinity purified polyclonal antibody against β amyloid  (Cell Signaling Technology Inc)
    95
    Cell Signaling Technology Inc affinity purified polyclonal antibody against β amyloid
    Regional and cellular distribution of GABA B1 in wild‐type and APP/PS1 mice . A‐H . Immunoreactivity for GABA B1 in the hippocampus of wild‐type and APP/PS1 mice at 12 months of age using a pre‐embedding immunoperoxidase method at the light microscopic level. In the CA1 and CA3 regions and dentate gyrus (DG), GABA B1 immunoreactivity was very similar both in the wild‐type and the APP/PS1 mice, regardless of accumulation <t>of</t> <t>amyloid</t> plaques (asterisks). Labeling for GABA B1 showed the highest intensity in the stratum lacunosum‐moleculare (slm) and molecular layer (ml) and weaker in the strata oriens (so) and radiatum (sr). Immunoreactivity for GABA B1 was also detected in interneurons throughout all layers (white arrows), with similar distribution pattern and labeling intensity in wild‐type and APP/PS1 mice. I,J . Immunoreactivity for β‐amyloid in wild‐type and APP/PS1 mice at 12 months of age, showing high accumulation of Aβ throughout all layers of the hippocampus. Abbreviations : CA1 region of the hippocampus; CA3, CA3 region of the hippocampus; DG, dentate gyrus; so, stratum oriens ; sp, stratum pyramidale ; sr, stratum radiatum ; slm, stratum lacunosum‐moleculare ; ml, molecular layer; gc, granule cell layer; h, hilus. Scale bars: A,B,I,J 200 µm; C‐H , 100 µm.
    Affinity Purified Polyclonal Antibody Against β Amyloid, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/affinity+purified+polyclonal+antibody+against+%CE%B2+amyloid/beta-Amyloid+Antibody/pmc07317930-46-1-20
    Average 95 stars, based on 1 article reviews
    affinity purified polyclonal antibody against β amyloid - by Bioz Stars, 2026-10
    95/100 stars
    		  Buy from Supplier

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    Regional and cellular distribution of GABA B1 in wild‐type and APP/PS1 mice . A‐H . Immunoreactivity for GABA B1 in the hippocampus of wild‐type and APP/PS1 mice at 12 months of age using a pre‐embedding immunoperoxidase method at the light microscopic level. In the CA1 and CA3 regions and dentate gyrus (DG), GABA B1 immunoreactivity was very similar both in the wild‐type and the APP/PS1 mice, regardless of accumulation of amyloid plaques (asterisks). Labeling for GABA B1 showed the highest intensity in the stratum lacunosum‐moleculare (slm) and molecular layer (ml) and weaker in the strata oriens (so) and radiatum (sr). Immunoreactivity for GABA B1 was also detected in interneurons throughout all layers (white arrows), with similar distribution pattern and labeling intensity in wild‐type and APP/PS1 mice. I,J . Immunoreactivity for β‐amyloid in wild‐type and APP/PS1 mice at 12 months of age, showing high accumulation of Aβ throughout all layers of the hippocampus. Abbreviations : CA1 region of the hippocampus; CA3, CA3 region of the hippocampus; DG, dentate gyrus; so, stratum oriens ; sp, stratum pyramidale ; sr, stratum radiatum ; slm, stratum lacunosum‐moleculare ; ml, molecular layer; gc, granule cell layer; h, hilus. Scale bars: A,B,I,J 200 µm; C‐H , 100 µm.

    Journal: Brain Pathology

    Article Title: Reduction in the neuronal surface of post and presynaptic GABA B receptors in the hippocampus in a mouse model of Alzheimer's disease

    doi: 10.1111/bpa.12802

    Figure Lengend Snippet: Regional and cellular distribution of GABA B1 in wild‐type and APP/PS1 mice . A‐H . Immunoreactivity for GABA B1 in the hippocampus of wild‐type and APP/PS1 mice at 12 months of age using a pre‐embedding immunoperoxidase method at the light microscopic level. In the CA1 and CA3 regions and dentate gyrus (DG), GABA B1 immunoreactivity was very similar both in the wild‐type and the APP/PS1 mice, regardless of accumulation of amyloid plaques (asterisks). Labeling for GABA B1 showed the highest intensity in the stratum lacunosum‐moleculare (slm) and molecular layer (ml) and weaker in the strata oriens (so) and radiatum (sr). Immunoreactivity for GABA B1 was also detected in interneurons throughout all layers (white arrows), with similar distribution pattern and labeling intensity in wild‐type and APP/PS1 mice. I,J . Immunoreactivity for β‐amyloid in wild‐type and APP/PS1 mice at 12 months of age, showing high accumulation of Aβ throughout all layers of the hippocampus. Abbreviations : CA1 region of the hippocampus; CA3, CA3 region of the hippocampus; DG, dentate gyrus; so, stratum oriens ; sp, stratum pyramidale ; sr, stratum radiatum ; slm, stratum lacunosum‐moleculare ; ml, molecular layer; gc, granule cell layer; h, hilus. Scale bars: A,B,I,J 200 µm; C‐H , 100 µm.

    Article Snippet: An affinity‐purified polyclonal antibody against β‐amyloid (ref #2454, detecting human Aβ‐40 and Aβ‐42 peptides) raised in rabbit was obtained from Cell Signalling Technology (Leiden, The Netherlands).

    Techniques: Labeling